Skip to Main Content U.S. Department of Energy
Energy and Environment Directorate
Page 745 of 1045

Staff Accomplishments

Biosensor Article Made Analytical Chemistry's Most Cited List

April 2007
Congratulations to ETD's Guodong Liu and Yuehe Lin on having their article on an innovative biosensor for pesticides and nerve agents make the 2006 Top 20 Most Cited Articles in Analytical Chemistry. Their article "Biosensor Based on Self-Assembling Acetylcholinesterase on Carbon Nanotubes for Flow Injection/Amperometric Detection of Organophosphate Pesticides and Nerve Agents" appeared in the February 1, 2006, issue of the journal. The article is already being cited by other researchers. The article discusses the construction of a sensor, composed of enzymes that self-assemble layer by layer onto tiny, hollow carbon tubes. When the sensor encounters organophosphates, the enzymes slow down. This reduced activity is transmitted as an electrochemical signal through the carbon nanotubes to an attached electrode. By reading the sensor's measurements, users can determine the concentration of organophosphates in environmental samples and biological fluids. Congratulations again, team!

Page 745 of 1045

Energy and Environment

Core Research Areas